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PD-1 Knockout Engineered T Cells for Advanced Lung Squamous Carcinoma
ChiCTR-OIC-17010390Phase 2Recruiting
- Sponsor
- The First Affiliated Hospital of USTC
- Start
- Jan 2017
- Modality
- CRISPR-Cas9 → CRISPR Systems → Programmable Nucleases → Gene Editing → Gene Therapies, TCR-Engineered T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
- Countries
- 1
01
Overview
Phase 2, open-label, single-arm trial of PD-1 knockout engineered T cells in Pulmonary squamous cell carcinoma, sponsored by The First Affiliated Hospital of USTC. Primary endpoint: Number of participants with adverse events and/or dose limiting toxicities. Started Jan 2017; status: recruiting.
02
Drugs
PD-1 knockout engineered T cells
03
Conditions
Pulmonary squamous cell carcinoma
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