Trial intelligence / Profile preview

Mycophenolate mofetil versus cyclophosphamide versus leflunomide for maintenance therapy in ANCA-associated systemic vasculitis with renal involvement in remission

ChiCTR-TRC-10000990Phase 4Completed

Sponsor
Ruijin Hospital
Start
Sep 2010
Modality
Small Molecules
Countries
1
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Overview

Phase 4, randomised, open-label trial in anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) comparing Cyclophosphamide + glucocorticoids, Leflunomide + glucocorticoids and Mycophenolate mofetil + glucocorticoids (3 arms). Primary endpoint: relapse rate. Started Sep 2010; status: completed.

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Drugs

cyclophosphamideleflunomidemycophenolate mofetil
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Conditions

anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV)

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