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Comparison of propofol, dexmedetomidine, and sevoflurane for organ protection during hepatectomy with or without inflow occlusion in patients with hepatocellular carcinoma and cirrhosis

ChiCTR-TRC-11001530Phase 4Completed

Sponsor
The First Affiliated Hospital of Sun Yat-sen University
Start
Jan 2011
Modality
Small Molecules
Countries
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Overview

Phase 4, open-label trial of propofol, dexmedetomidine and sevoflurane in hepatocellular carcinoma (HCC) and Cirrhosis (6 arms), sponsored by The First Affiliated Hospital of Sun Yat-sen University. Primary endpoints: Cardiac, liver, renal, intestinal barrier, immune, and inflammatory blood biomarkers and Liver tissue pathology and apoptosis markers. Started Jan 2011; status: completed.

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Drugs

propofoldexmedetomidinesevoflurane
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Conditions

hepatocellular carcinoma (HCC)Cirrhosis

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