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TGP added to methotrexate and leflunomide for liver function protection in rheumatoid arthritis
ChiCTR-TRC-11001789Phase 4Completed
- Sponsor
- The First Affiliated Hospital of USTC
- Start
- Nov 2011
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 4, open-label trial of total glucosides of paeony, methotrexate and leflunomide in rheumatoid arthritis (RA) (2 arms), sponsored by The First Affiliated Hospital of USTC. Primary endpoints: Alanine aminotransferase and Aspartate aminotransferase. Started Nov 2011; status: completed.
02
Drugs
total glucosides of paeonymethotrexateleflunomide
03
Conditions
rheumatoid arthritis (RA)
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