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Chinese herbal medicine versus methotrexate plus sulfasalazine in rheumatoid arthritis patients with low response to methotrexate-based therapy
ChiCTR-TRC-13002981Phase 4Completed
- Sponsor
- Institute of Basic Research in Clinical Medicine
- Start
- Jan 2013
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 4, randomised, double-blind trial of tripterygium wilfordii polyglycosides, Yi Shen Juan Bi, methotrexate and 5-aminosalicylic acid + sulphasalazine in rheumatoid arthritis (RA) (2 arms), sponsored by Institute of Basic Research in Clinical Medicine. Primary endpoints: Rest pain, Joint tenderness and 7 more. Started Jan 2013; status: completed.
02
Drugs
tripterygium wilfordii polyglycosidesYi Shen Juan Bimethotrexate5-aminosalicylic acid + sulphasalazine
03
Conditions
rheumatoid arthritis (RA)
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