Early intravenous vitamin C + thiamine + hydrocortisone for septic shock

Phase 4 trial of ascorbic acid, thiamine and hydrocortisone in septic shock and sepsis (2 arms), sponsored by The Sixth Affiliated Hospital of Kunming Medical University. Primary endpoints: Change in Sequential Organ Failure Assessment score at 72 hours and Requirement for renal replacement therapy in participants with acute kidney injury. Planned start May 2018; status: not yet recruiting.