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Dexmedetomidine added to propofol-remifentanil anesthesia for postoperative cognitive function after ureteroscopic holmium laser lithotripsy in older adults

ChiCTR1900021254Phase 4Completed

Sponsor
Affiliated Hospital of North Sichuan Medical College
Start
Jan 2019
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
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Overview

Phase 4, randomised, open-label trial in post-operative cognitive decline (POCD) comparing Propofol + remifentanil anesthesia with Dexmedetomidine + propofol + remifentanil anesthesia (2 arms). Primary endpoints: Digital memory, Mini-mental state examination and 2 more. Started Jan 2019; status: completed.

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Drugs

dexmedetomidinepropofolremifentanil
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Conditions

post-operative cognitive decline (POCD)

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