Trial intelligence / Profile preview

Palbociclib + letrozole versus EC followed by docetaxel as neoadjuvant therapy for inoperable postmenopausal ER-positive low-Ki67 breast cancer

ChiCTR1900026493Phase 4Not yet recruiting

Sponsor
Shengjing Hospital of China Medical University
Start
Dec 2019
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 4, randomised, double-blind trial in breast cancer comparing Palbociclib + letrozole with Epirubicin + cyclophosphamide followed by docetaxel (2 arms). Primary endpoint: Efficacy. Planned start Dec 2019; status: not yet recruiting.

02

Drugs

palbociclibletrozoleepirubicincyclophosphamidedocetaxel
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Conditions

breast cancer

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