Trial intelligence / Profile preview

TKI with or without statins for refractory generalized chronic graft-versus-host disease

ChiCTR1900026602Phase 4Recruiting

Sponsor
Medical Center of Hematology, Xinqiao Hospital, Army Medical University
Start
Oct 2019
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
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Overview

Phase 4, open-label trial of imatinib, dasatinib and atorvastatin in chronic graft-versus-host disease (cGVHD) (2 arms), sponsored by Medical Center of Hematology, Xinqiao Hospital, Army Medical University. Primary endpoints: Severity score of chronic graft-versus-host disease, Target organ types of chronic graft-versus-host disease and 5 more. Started Oct 2019; status: recruiting.

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Drugs

imatinibdasatinibatorvastatin
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Conditions

chronic graft-versus-host disease (cGVHD)

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