Trial intelligence / Profile preview

Vitamin K1 route comparison for excessive warfarin anticoagulation after mechanical valve replacement

ChiCTR2000029013Phase 4Recruiting

Sponsor
West China Hospital of Sichuan University
Start
Jan 2020
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, randomised, open-label trial of phytomenadione and warfarin in Cardiac valve disease (VHD) (4 arms), sponsored by West China Hospital of Sichuan University. Primary endpoints: INR, warfarin-related gene polymorphism and 2 more. Started Jan 2020; status: recruiting.

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Drugs

phytomenadionewarfarin
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Conditions

Cardiac valve disease (VHD)

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