Trial intelligence / Profile preview

XELOX + regorafenib + PD-1 antibody for first-line HER2-negative advanced gastric or gastroesophageal junction adenocarcinoma

ChiCTR2000033070Phase 2Recruiting

Sponsor
Shanghai East Hospital
Start
May 2020
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of capecitabine, oxaliplatin, regorafenib and PD-1 Monoclonal Antibody in gastric adenocarcinoma and gastroesophageal junction adenocarcinoma, sponsored by Shanghai East Hospital. Primary endpoint: Objective response rate. Started May 2020; status: recruiting.

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Drugs

capecitabineoxaliplatinregorafenibPD-1 Monoclonal Antibody
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Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinoma

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