Trial intelligence / Profile preview

Different-dose nalmefene combined with sufentanil in elderly perioperative patients

ChiCTR2000034772Phase 4Recruiting

Sponsor
The First Affiliated Hospital of Guangxi Medical University
Start
Jul 2020
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
Countries
1
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Overview

Phase 4, randomised, open-label trial of nalmefene and sufentanil in postoperative pain, post-operative cognitive decline (POCD), Postoperative gastrointestinal dysfunction (POGD) and 1 more (2 arms), sponsored by The First Affiliated Hospital of Guangxi Medical University. Primary endpoints: Time to Aldrete score at least 9 after PACU admission, Incidence of postoperative gastrointestinal dysfunction and 1 more. Started Jul 2020; status: recruiting.

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Drugs

nalmefenesufentanil
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Conditions

postoperative painpost-operative cognitive decline (POCD)Postoperative gastrointestinal dysfunction (POGD)postoperative nausea and vomiting (PONV)

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