Trial intelligence / Profile preview

Pyrotinib + SHR6390 + letrozole neoadjuvant trial in stage II-III triple-positive breast cancer

ChiCTR2000034827Phase 3Not yet recruiting

Sponsor
Shengjing Hospital of China Medical University
Start
Jul 2020
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
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Overview

Phase 3, open-label, single-arm trial of pyrotinib, dalpiciclib and letrozole in breast cancer, sponsored by Shengjing Hospital of China Medical University. Primary endpoint: Total pathological complete response. Planned start Jul 2020; status: not yet recruiting.

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Drugs

pyrotinibdalpiciclibletrozole
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Conditions

breast cancer

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