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Phase II umbrella neoadjuvant targeted/immunotherapy plus chemotherapy in stage III NSCLC

ChiCTR2000036594Phase 2Not yet recruiting

Sponsor
Shanghai Pulmonary Hospital
Start
Oct 2020
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of osimertinib, crizotinib and durvalumab in non-small cell lung cancer (NSCLC) (5 arms), sponsored by Shanghai Pulmonary Hospital. Primary endpoints: Pathological remission rate, Objective response rate and 1 more. Planned start Oct 2020; status: not yet recruiting.

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Drugs

osimertinibcrizotinibdurvalumab
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Conditions

non-small cell lung cancer (NSCLC)

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