Trial intelligence / Profile preview

Toripalimab plus axitinib neoadjuvant therapy in VHL-associated clear cell renal cell carcinoma

ChiCTR2000037024Phase 4Recruiting

Sponsor
Renji Hospital
Start
Oct 2020
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
Countries
1
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Overview

Phase 4, open-label, single-arm trial of toripalimab and axitinib in clear cell renal cell carcinoma (ccRCC) and von Hippel–Lindau disease (VHL), sponsored by Renji Hospital. Primary endpoints: Objective response rate of kidney tumors at week 12, Safety – incidence of adverse events and 1 more. Started Oct 2020; status: recruiting.

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Drugs

toripalimabaxitinib
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Conditions

clear cell renal cell carcinoma (ccRCC)von Hippel–Lindau disease (VHL)

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