Trial intelligence / Profile preview

FOLFOXIRI plus cetuximab versus FOLFOXIRI plus bevacizumab for conversion therapy in RAS/BRAF wild-type right-sided colon cancer with initially unresectable liver-only metastases

ChiCTR2000037711Phase 4Recruiting

Sponsor
Zhongshan Hospital, Fudan University
Start
Oct 2020
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, randomised, open-label trial of cetuximab, bevacizumab, fluorouracil, folinic acid, oxaliplatin and 1 more in colon cancer and colorectal cancer (CRC) (2 arms), sponsored by Zhongshan Hospital, Fudan University. Primary endpoint: conversion-to-resection rate. Started Oct 2020; status: recruiting.

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Drugs

cetuximabbevacizumabfluorouracilfolinic acidoxaliplatin
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Conditions

colon cancercolorectal cancer (CRC)

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