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ARNI versus ARB after primary valvular regurgitation surgery for residual left ventricular remodeling

ChiCTR2000038895Phase 4Recruiting

Sponsor
West China Hospital of Sichuan University
Start
Oct 2020
Modality
Small Molecules
Countries
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Overview

Phase 4, randomised, open-label trial of sacubitril + valsartan in Left ventricular remodeling (LVR), aortic insufficiency (AI) and mitral regurgitation (MR) (4 arms), sponsored by West China Hospital of Sichuan University. Primary endpoints: Left ventricular ejection fraction and Left ventricular end-diastolic dimension. Started Oct 2020; status: recruiting.

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Drugs

sacubitril + valsartan
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Conditions

Left ventricular remodeling (LVR)aortic insufficiency (AI)mitral regurgitation (MR)

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