Trial intelligence / Profile preview

Initumab-based first-line treatment for HER2-positive advanced gastric or gastroesophageal junction adenocarcinoma

ChiCTR2100041919Phase 2Recruiting

Sponsor
Shandong Provincial Qianfoshan Hospital
Start
Jan 2021
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of initumab, pyrotinib, oxaliplatin, capecitabine and paclitaxel in gastric adenocarcinoma and gastroesophageal junction adenocarcinoma (2 arms), sponsored by Shandong Provincial Qianfoshan Hospital. Primary endpoint: Progression-free survival. Started Jan 2021; status: recruiting.

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Drugs

initumabpyrotiniboxaliplatincapecitabinepaclitaxel
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Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinoma

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