Trial intelligence / Profile preview

COIN trial of low-dose colchicine for small abdominal aortic aneurysm growth

ChiCTR2100046776Phase 4Recruiting

Sponsor
Guangdong Provincial People's Hospital
Start
Sep 2021
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
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Overview

Phase 4, randomised, double-blind trial in abdominal aortic aneurysm (AAA) comparing Colchicine group with Placebo group (2 arms). Primary endpoints: Change in maximum abdominal aortic aneurysm diameter by angiography and Change in maximum abdominal aortic aneurysm diameter by ultrasound. Started Sep 2021; status: recruiting.

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Drugs

colchicine
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Conditions

abdominal aortic aneurysm (AAA)

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