Trial intelligence / Profile preview

AC-CHOP for de-novo PTCL with TFH phenotype

ChiCTR2100047467Phase 2Recruiting

Sponsor
West China Hospital of Sichuan University
Start
Jul 2021
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of azacitidine, tucidinostat, cyclophosphamide, doxorubicin, vincristine and 1 more in T-cell lymphoma follicular helper (TFHL), angioimmunoblastic T-cell lymphoma (AITL), follicular T-cell lymphoma (FTCL) and 1 more, sponsored by West China Hospital of Sichuan University. Primary endpoint: complete remission rate. Started Jul 2021; status: recruiting.

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Drugs

azacitidinetucidinostatcyclophosphamidedoxorubicinvincristine
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Conditions

T-cell lymphoma follicular helper (TFHL)angioimmunoblastic T-cell lymphoma (AITL)follicular T-cell lymphoma (FTCL)peripheral T-cell lymphoma not otherwise specified (PTCL-NOS)

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