Trial intelligence / Profile preview

AG chemotherapy + tislelizumab + regorafenib + GM-CSF for neoadjuvant treatment of resectable or borderline resectable pancreatic cancer

ChiCTR2100049343Phase 2Not yet recruiting

Sponsor
First Affiliated Hospital of Soochow University
Start
Oct 2021
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, open-label, single-arm trial of tislelizumab, regorafenib, paclitaxel, gemcitabine and sargramostim in pancreatic adenocarcinoma (PDAC), sponsored by First Affiliated Hospital of Soochow University. Primary endpoints: Objective response rate and Major pathological response rate. Planned start Oct 2021; status: not yet recruiting.

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Drugs

tislelizumabregorafenibpaclitaxelgemcitabinesargramostim
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Conditions

pancreatic adenocarcinoma (PDAC)

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