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Phase I/II study of large-fraction radiotherapy followed by sintilimab plus donafenib for hepatocellular carcinoma with portal vein tumor thrombus

ChiCTR2100051537Phase 2Not yet recruiting

Sponsor
The 2nd Affiliated Hospital of Chongqing Medical University
Start
Oct 2021
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of sintilimab and donafenib in hepatocellular carcinoma (HCC), sponsored by The 2nd Affiliated Hospital of Chongqing Medical University. Primary endpoints: Maximum tolerated dose and Progression-free survival. Planned start Oct 2021; status: not yet recruiting.

02

Drugs

sintilimabdonafenib
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Conditions

hepatocellular carcinoma (HCC)

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