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Phase Ib/II trial of BEBT-908 and BEBT-109 in advanced EGFR-mutant NSCLC after third-generation EGFR-TKI

ChiCTR2100054223Phase 2Recruiting

Sponsor
Hunan Cancer Hospital
Start
Dec 2021
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
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Overview

Phase 2, open-label trial of ifupinostat and BEBT-109 in non-small cell lung cancer (NSCLC) (3 arms), sponsored by Hunan Cancer Hospital. Primary endpoints: Objective Response Rate, Pharmacokinetics and 6 more. Started Dec 2021; status: recruiting.

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Drugs

ifupinostatBEBT-109
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Conditions

non-small cell lung cancer (NSCLC)

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