Trial intelligence / Profile preview

Cardiovascular benefits and safety of sacubitril-valsartan in CKD stage 5 with refractory hypertension

ChiCTR2200058161Phase 4Not yet recruiting

Sponsor
The First Affiliated Hospital of Guangxi Medical University
Start
Apr 2022
Modality
Small Molecules
Countries
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Overview

Phase 4, open-label, single-arm trial of sacubitril + valsartan in chronic kidney disease (CKD), hypertension (HTN) and heart failure (HF), sponsored by The First Affiliated Hospital of Guangxi Medical University. Primary endpoints: Blood pressure at 3 months and NYHA grading of cardiac function at 3 months. Planned start Apr 2022; status: not yet recruiting.

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Drugs

sacubitril + valsartan
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Conditions

chronic kidney disease (CKD)hypertension (HTN)heart failure (HF)

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