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Zanubrutinib + cyclophosphamide + dexamethasone for newly diagnosed or progressive Waldenstrom macroglobulinemia

ChiCTR2200058236Phase 4Not yet recruiting

Sponsor
Beijing Chaoyang Hospital, Capital Medical University
Start
Mar 2022
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, open-label, single-arm trial of zanubrutinib, cyclophosphamide and dexamethasone in Waldenström macroglobulinemia (WM), sponsored by Beijing Chaoyang Hospital, Capital Medical University. Primary endpoints: Objective response rate and Progression-free survival. Planned start Mar 2022; status: not yet recruiting.

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Drugs

zanubrutinibcyclophosphamidedexamethasone
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Conditions

Waldenström macroglobulinemia (WM)

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