Trial intelligence / Profile preview

Phase Ib/II study of CAPOX + sintilimab + bevacizumab as first-line therapy for recurrent or metastatic gastric or gastroesophageal junction adenocarcinoma

ChiCTR2200059975Phase 2Not yet recruiting

Sponsor
West China Hospital of Sichuan University
Start
May 2022
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of sintilimab, bevacizumab, capecitabine and oxaliplatin in gastric adenocarcinoma and gastroesophageal junction adenocarcinoma, sponsored by West China Hospital of Sichuan University. Primary endpoints: Dose-limiting toxicity incidence and Objective response rate. Planned start May 2022; status: not yet recruiting.

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Drugs

sintilimabbevacizumabcapecitabineoxaliplatin
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Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinoma

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