Trial intelligence / Profile preview

RC48 plus tislelizumab as neoadjuvant therapy in HER2-positive muscle-invasive bladder cancer

ChiCTR2200060153Phase 2Not yet recruiting

Sponsor
West China Hospital of Sichuan University
Start
May 2022
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of disitamab vedotin and tislelizumab in transitional cell carcinoma of the bladder (TCC) and bladder cancer, sponsored by West China Hospital of Sichuan University. Primary endpoints: Clinical complete response rate and Pathologic complete response rate. Planned start May 2022; status: not yet recruiting.

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Drugs

disitamab vedotintislelizumab
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Conditions

transitional cell carcinoma of the bladder (TCC)bladder cancer

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