Trial intelligence / Profile preview

Chemotherapy-free BTK inhibitor + PD-1 + XPO1 regimen in relapsed/refractory DLBCL

ChiCTR2200060630Phase 2Not yet recruiting

Sponsor
Sichuan Provincial People's Hospital
Start
May 2022
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of zanubrutinib in diffuse large B-cell lymphoma (DLBCL), sponsored by Sichuan Provincial People's Hospital. Primary endpoint: overall response rate at 2 months. Planned start May 2022; status: not yet recruiting.

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Drugs

zanubrutinib
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Conditions

diffuse large B-cell lymphoma (DLBCL)

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