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Tislelizumab plus pemetrexed, carboplatin, and bevacizumab after EGFR-TKI failure in T790M-negative EGFR-mutant non-squamous NSCLC

ChiCTR2200062038Phase 2Recruiting

Sponsor
Xuanwu Hospital
Start
Aug 2022
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of tislelizumab, pemetrexed, carboplatin and bevacizumab in non-small cell lung cancer (NSCLC), sponsored by Xuanwu Hospital. Primary endpoint: Objective response rate. Started Aug 2022; status: recruiting.

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Drugs

tislelizumabpemetrexedcarboplatinbevacizumab
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Conditions

non-small cell lung cancer (NSCLC)

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