Trial intelligence / Profile preview

Polymyxin B plasma and lung penetration in HAP/VAP due to carbapenem-resistant Gram-negative bacilli

ChiCTR2200062227Phase 4Not yet recruiting

Sponsor
Huashan Hospital
Start
Jul 2022
Modality
Small Molecules, Peptides
Countries
1
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Overview

Phase 4, open-label, single-arm trial of polymyxin B in hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), Gram-negative pneumonia and 1 more, sponsored by Huashan Hospital. Primary endpoints: Polymyxin B concentration and lung penetration in blood and pulmonary epithelial lining fluid and Pharmacokinetic characteristics of polymyxin B in plasma. Planned start Jul 2022; status: not yet recruiting.

02

Drugs

polymyxin B
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Conditions

hospital-acquired pneumonia (HAP)ventilator-associated pneumonia (VAP)Gram-negative pneumoniapneumonia

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