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Selinexor + bortezomib + lenalidomide + dexamethasone for newly diagnosed high-risk multiple myeloma

ChiCTR2200062860Phase 4Recruiting

Sponsor
Qingdao Municipal Hospital
Start
Aug 2022
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Reversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, Small Molecules
Countries
1
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Overview

Phase 4, open-label, single-arm trial of selinexor, bortezomib, lenalidomide and dexamethasone in multiple myeloma (MM) and plasma cell leukaemia (PCL), sponsored by Qingdao Municipal Hospital. Primary endpoints: Objective remission rate and Minimal residual disease negative rate. Started Aug 2022; status: recruiting.

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Drugs

selinexorbortezomiblenalidomidedexamethasone
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Conditions

multiple myeloma (MM)plasma cell leukaemia (PCL)

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