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Phase II neoadjuvant FLOT versus FLOT + sintilimab versus FLOT + sintilimab + apatinib for locally advanced gastric or gastroesophageal junction adenocarcinoma

ChiCTR2200063760Phase 2Recruiting

Sponsor
Second Hospital of Lanzhou University
Start
Aug 2022
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of Rivoceranib, sintilimab and FLOT in gastric adenocarcinoma and gastroesophageal junction adenocarcinoma (3 arms), sponsored by Second Hospital of Lanzhou University. Primary endpoint: pathological complete response rate. Started Aug 2022; status: recruiting.

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Drugs

RivoceranibsintilimabFLOT
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Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinoma

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