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Phase IIIa trial of heterologous booster SARS-CoV-2 variant mRNA vaccine after prior inactivated COVID-19 vaccination

ChiCTR2200065736Phase 3Not yet recruiting

Sponsor
The First Affiliated Hospital of Guangzhou Medical University
Start
Nov 2022
Modality
Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes, mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
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Overview

Phase 3, randomised trial of SARS-CoV-2 variants mRNA vaccine and recombinant COVID-19 (XBB) trimer protein vaccine in coronavirus disease 2019 (COVID-19) (2 arms), sponsored by The First Affiliated Hospital of Guangzhou Medical University. Primary endpoint: Live virus neutralizing antibody titers against SARS-CoV-2 current major endemic strain. Planned start Nov 2022; status: not yet recruiting.

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Drugs

SARS-CoV-2 variants mRNA vaccinerecombinant COVID-19 (XBB) trimer protein vaccine
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Conditions

coronavirus disease 2019 (COVID-19)

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