Trial intelligence / Profile preview

PISTIAS trial of evolocumab plus statin therapy for symptomatic intracranial artery stenosis

ChiCTR2300068868Phase 4Recruiting

Sponsor
Peking Union Medical College Hospital
Start
Aug 2023
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 4, randomised trial of evolocumab, rosuvastatin, atorvastatin and ezetimibe in cerebral arteriosclerosis, ischemic stroke and transient ischaemic attack (TIA) (2 arms), sponsored by Peking Union Medical College Hospital. Primary endpoint: Plaque burden. Started Aug 2023; status: recruiting.

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Drugs

evolocumabrosuvastatinatorvastatinezetimibe
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Conditions

cerebral arteriosclerosisischemic stroketransient ischaemic attack (TIA)

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