Trial intelligence / Profile preview

RC48 plus pyrotinib for HER2-positive advanced breast cancer with brain metastases

ChiCTR2300068946Phase 2Recruiting

Sponsor
Tianjin Medical University Cancer Institute and Hospital Airport Hospital
Start
Mar 2023
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of disitamab vedotin and pyrotinib in breast cancer (2 arms), sponsored by Tianjin Medical University Cancer Institute and Hospital Airport Hospital. Primary endpoint: Central nervous system objective response rate. Started Mar 2023; status: recruiting.

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Drugs

disitamab vedotinpyrotinib
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Conditions

breast cancer

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