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Opioid-free anesthesia with esketamine + dexmedetomidine + sevoflurane for small and medium-sized surgery

ChiCTR2300069061Phase 4Not yet recruiting

Sponsor
The Affiliated Hospital of Qingdao University
Start
Mar 2023
Modality
Small Molecules
Countries
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Overview

Phase 4, randomised trial of esketamine, dexmedetomidine and sevoflurane in perioperative pain, postoperative nausea and vomiting (PONV) and respiratory failure (2 arms), sponsored by The Affiliated Hospital of Qingdao University. Primary endpoints: Incidence of postoperative nausea and vomiting (PONV) and rescue treatment, Postoperative respiratory function and 1 more. Planned start Mar 2023; status: not yet recruiting.

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Drugs

esketaminedexmedetomidinesevoflurane
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Conditions

perioperative painpostoperative nausea and vomiting (PONV)respiratory failure

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