Trial intelligence / Profile preview

SMET12 plus toripalimab in EGFR-positive advanced solid tumors

ChiCTR2300069123Phase 2Recruiting

Sponsor
Fujian Medical University Cancer Hospital
Start
Mar 2023
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label trial of SMET12 and toripalimab in melanoma, head and neck squamous cell carcinoma (HNSCC), transitional cell carcinoma (TCC) and 4 more (2 arms), sponsored by Fujian Medical University Cancer Hospital. Primary endpoints: Efficacy, Objective response rate (ORR) and 3 more. Started Mar 2023; status: recruiting.

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Drugs

SMET12toripalimab
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Conditions

melanomahead and neck squamous cell carcinoma (HNSCC)transitional cell carcinoma (TCC)gastric cancer (GC)Esophageal Squamous Cell Carcinoma (ESCC)

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