Trial intelligence / Profile preview

Zanubrutinib plus intrathecal chemotherapy for prevention of central nervous system recurrence in high-risk diffuse large B-cell lymphoma

ChiCTR2300072657Phase 4Recruiting

Sponsor
Sir Run-Run Shaw Hospital
Start
Mar 2023
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
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Overview

Phase 4, open-label, single-arm trial of zanubrutinib in diffuse large B-cell lymphoma (DLBCL), sponsored by Sir Run-Run Shaw Hospital. Primary endpoint: Cumulative central nervous system recurrence rate over 2 years. Started Mar 2023; status: recruiting.

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Drugs

zanubrutinib
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Conditions

diffuse large B-cell lymphoma (DLBCL)

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