Trial intelligence / Profile preview

MRD-guided deferred adjuvant therapy in resectable early-stage colon cancer

ChiCTR2300072958Phase 2Not yet recruiting

Sponsor
Sun Yat-sen University Cancer Center
Start
Jul 2023
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of capecitabine, oxaliplatin, irinotecan, folinic acid and fluorouracil in colon adenocarcinoma (4 arms), sponsored by Sun Yat-sen University Cancer Center. Primary endpoints: Overall survival in MRD-negative groups, Overall survival in MRD-positive groups and 2 more. Planned start Jul 2023; status: not yet recruiting.

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Drugs

capecitabineoxaliplatinirinotecanfolinic acidfluorouracil
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Conditions

colon adenocarcinoma

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