Trial intelligence / Profile preview

VAP regimen (palbociclib + venetoclax + azacitidine) in NUP98-R positive childhood AML

ChiCTR2300074396Phase 2Recruiting

Sponsor
Union Hospital
Start
Aug 2023
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of palbociclib, venetoclax and azacitidine in acute myeloid leukemia (AML), sponsored by Union Hospital. Primary endpoint: Remission rate after one course of VAP regimen treatment. Started Aug 2023; status: recruiting.

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Drugs

palbociclibvenetoclaxazacitidine
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Conditions

acute myeloid leukemia (AML)

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