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Esketamine versus opioid anesthesia for recovery quality and postoperative anxiety/depression after laparoscopic total hysterectomy

ChiCTR2300075661Phase 4Not yet recruiting

Sponsor
Changzhi People's Hospital
Start
Jul 2023
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
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Overview

Phase 4, open-label trial of esketamine, sufentanil, remifentanil, propofol and rocuronium in postoperative pain, anxiety disorder and postoperative depression (2 arms), sponsored by Changzhi People's Hospital. Primary endpoints: Postoperative Recovery Quality Scale (QoR-40), Hospital Anxiety and Depression Scale (HADS-A/HADS-D) and 2 more. Planned start Jul 2023; status: not yet recruiting.

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Drugs

esketaminesufentanilremifentanilpropofolrocuronium
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Conditions

postoperative painanxiety disorderpostoperative depression

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