Trial intelligence / Profile preview

Local radiation dose escalation with irinotecan-capecitabine total neoadjuvant therapy for organ preservation in low rectal cancer

ChiCTR2400080595Phase 2Not yet recruiting

Sponsor
Henan Cancer Hospital
Start
Feb 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of irinotecan and capecitabine in rectal adenocarcinoma and rectal cancer, sponsored by Henan Cancer Hospital. Primary endpoint: Complete clinical response rate after treatment. Planned start Feb 2024; status: not yet recruiting.

02

Drugs

irinotecancapecitabine
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Conditions

rectal adenocarcinomarectal cancer

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