Trial intelligence / Profile preview

PCSK9 inhibitor (evolocumab) plus atorvastatin for acute symptomatic intracranial arterial stenosis

ChiCTR2400081186Phase 4Recruiting

Sponsor
Sun Yat-sen Memorial Hospital
Start
Feb 2024
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 4, randomised, open-label trial of evolocumab in cerebrovascular disease, Cerebral atherosclerotic stenosis (ICAD), ischemic stroke and 1 more (2 arms), sponsored by Sun Yat-sen Memorial Hospital. Primary endpoint: Atherosclerotic plaque morphological assessment. Started Feb 2024; status: recruiting.

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Drugs

evolocumab
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Conditions

cerebrovascular diseaseCerebral atherosclerotic stenosis (ICAD)ischemic stroketransient ischaemic attack (TIA)

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