Trial intelligence / Profile preview

Sailing A: Peginterferon alfa-2b plus nucleos(t)ide analogues vs nucleos(t)ide analogue monotherapy in HBeAg-positive chronic hepatitis B

ChiCTR2400082960Phase 4Recruiting

Sponsor
The First People's Hospital of Yunnan Province
Start
Apr 2024
Modality
Small Molecules, Cytokines & Interferons → Recombinant Proteins and Enzymes, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Countries
1
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Overview

Phase 4, open-label trial of peginterferon alfa-2b, entecavir, tenofovir disoproxil fumarate and tenofovir alafenamide in Chronic Hepatitis B (CHB) (2 arms), sponsored by The First People's Hospital of Yunnan Province. Primary endpoint: HBeAg seroconversion rate. Started Apr 2024; status: recruiting.

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Drugs

peginterferon alfa-2bentecavirtenofovir disoproxil fumaratetenofovir alafenamide
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Conditions

Chronic Hepatitis B (CHB)

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