Trial intelligence / Profile preview

High-dose furmonertinib plus chemotherapy as first-line treatment for EGFR-mutant NSCLC with CNS metastases

ChiCTR2400084196Phase 2Not yet recruiting

Sponsor
Anhui Provincial Tumor Hospital
Start
May 2024
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of furmonertinib, pemetrexed and carboplatin in non-small cell lung cancer (NSCLC) and central nervous system metastases, sponsored by Anhui Provincial Tumor Hospital. Primary endpoint: Progression-free survival. Planned start May 2024; status: not yet recruiting.

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Drugs

furmonertinibpemetrexedcarboplatin
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Conditions

non-small cell lung cancer (NSCLC)central nervous system metastases

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