Trial intelligence / Profile preview

Distamab vedotin + carboplatin + bevacizumab for HER2-expressing platinum-sensitive recurrent ovarian cancer after prior PARP inhibitor treatment

ChiCTR2400084761Phase 4Not yet recruiting

Sponsor
Fudan University Shanghai Cancer Center
Start
May 2024
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, open-label, single-arm trial of disitamab vedotin, carboplatin and bevacizumab in ovarian cancer, fallopian tube cancer (PFTC) and primary peritoneal cancer (PPC), sponsored by Fudan University Shanghai Cancer Center. Primary endpoint: Objective response rate. Planned start May 2024; status: not yet recruiting.

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Drugs

disitamab vedotincarboplatinbevacizumab
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Conditions

ovarian cancerfallopian tube cancer (PFTC)primary peritoneal cancer (PPC)

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