Trial intelligence / Profile preview

Subretinal vs intravitreal tPA + Conbercept + C3F8 for acute submacular hemorrhage

ChiCTR2400089058Phase 4Recruiting

Sponsor
Dongguan Guangming Ophthalmology Hospital
Start
Aug 2024
Modality
Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes, Small Molecules, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 4, open-label trial of conbercept, tissue-plasminogen activator and perflutren in submacular hemorrhage (SMH), exudative macular degeneration and polypoidal choroidal vasculopathy (PCV) (2 arms), sponsored by Dongguan Guangming Ophthalmology Hospital. Primary endpoints: Displacement and absorption of submacular hemorrhage, Visual acuity and 3 more. Started Aug 2024; status: recruiting.

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Drugs

conbercepttissue-plasminogen activatorperflutren
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Conditions

submacular hemorrhage (SMH)exudative macular degenerationpolypoidal choroidal vasculopathy (PCV)

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