Trial intelligence / Profile preview

HST101 (Ledaceibup) in Chinese patients with hypercholesterolemia

ChiCTR2400089193Phase 3Not yet recruiting

Sponsor
Peking University First Hospital
Start
Sep 2024
Modality
Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 3, randomised, double-blind trial in hypercholesterolemia and familial hypercholesterolemia (FH) comparing HST101 with Placebo (2 arms). Primary endpoints: Percent change from baseline in LDL-C level at week 12 (Friedewald formula) and Percent change from baseline in mean LDL-C levels at weeks 10 and 12 (Friedewald formula). Planned start Sep 2024; status: not yet recruiting.

02

Drugs

lerodalcibep
03

Conditions

hypercholesterolemiafamilial hypercholesterolemia (FH)

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