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OB756 Phase Ib/II study in myelofibrosis

ChiCTR2400090838Phase 2Completed

Sponsor
First Affiliated Hospital, Zhejiang University School of Medicine
Start
Oct 2024
Modality
Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of bewintinib in primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (PPV-MF) and myelofibrosis (MF) (8 arms), sponsored by First Affiliated Hospital, Zhejiang University School of Medicine. Primary endpoints: p-STAT3 inhibition and Proportion of subjects with spleen volume reduction of at least 35% at 24 weeks. Started Oct 2024; status: completed.

02

Drugs

bewintinib
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Conditions

primary myelofibrosis (PMF)post-polycythemia vera myelofibrosis (PPV-MF)myelofibrosis (MF)

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