Trial intelligence / Profile preview

Phase 3 study of subcutaneous MK-3475A versus intravenous pembrolizumab in first-line metastatic PD-L1-high non-small cell lung cancer

ChiCTR2400092825Phase 3Not yet recruiting

Sponsor
Peking Union Medical College Hospital
Start
Nov 2024
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Therapeutic Enzymes → Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 3, randomised, open-label trial of pembrolizumab and hyaluronidase in non-small cell lung cancer (NSCLC) (2 arms), sponsored by Peking Union Medical College Hospital. Primary endpoints: Cycle 1 AUC0-6 weeks and Cycle 3 trough concentration. Planned start Nov 2024; status: not yet recruiting.

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Drugs

pembrolizumabhyaluronidase
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Conditions

non-small cell lung cancer (NSCLC)

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